School of Applied Science Student Projects

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Understanding the Mechanism of Hepatocellular Carcinoma to Develop Better Treatments

Liver cancer is the second leading cause of cancer-related death globally and hepatocellular carcinoma (HCC) accounts for 90% of all primary liver cancers in humans. Currently, drugs approved for the treatment of HCC have limited effectiveness and poor survival benefits in patients.  Hence there is a need to develop alternative therapies with better clinical outcomes.  However, to do so, it is important to first understand the disease mechanism in order to develop better treatment options for HCC. 

 

Justin Tang Jit Hin, a Diploma in Pharmaceutical Science graduate from the class of 2020, completed his 26-week Student Internship Programme (SIP) at The N.1 Institute for Health (N.1), National University of Singapore.  Being in this final year, he also worked on his Major Project there at N.1, studying the role of STAT3, a protein that is involved in many types of cancers such as in HCC.  During his internship, Justin wrote a review paper on “JAK/STAT Signaling in Hepatocellular Carcinoma” that was subsequently published in the reputed scientific journal, Hepatic Oncology in March 2020.

Making Sustainable Alternative of Dairy Free Soy Frozen Yoghurt

   

Frozen yoghurt has been gaining popularity in Singapore with stores serving artisanal soft serve frozen yoghurts.  Though still at the infancy stage in the Asian market, frozen yoghurts are also packed in tubs and sold in supermarkets but with limited variety.  Most brands claim health benefits stating that they contain live cultures or probiotics, but in reality some are high in sugar though lower in fat.  Thus they lack the health benefits other than the presence of probiotics. In fact the survival of probiotics in frozen yoghurts is important to support the therapeutic image of the product since they need to impart the health benefits such as the regulation of intestinal flora and improvement of the immune system.

Students from the Diploma in Applied Food Science and Nutrition did their Major Project on developing a novel soy-based frozen yoghurt using a symbiotic approach (that is using probiotic culture and prebiotics).   Ensuring that a minimum viable microbe count was met in the frozen yoghurt, this allowed their product to substantiate the benefits of probiotics to human health when consumed.  The project also reviewed the synergistic effects of the different food additives used in the formulation, as well as effects of other factors, including fermentation time, post acidification, and microbial count.  Various tests were also performed such as pH, viscosity, overrun, meltdown and sensory evaluation.  The survivability of probiotics in frozen yoghurt was also evaluated and tested via microbial testing.  During which, it was discovered that inulin was able to increase the survivability of the probiotics in the dairy frozen yoghurt at freezing temperature.  It was also able to impart a satisfactory mouthfeel and texture that mimics the bulking property of sugar.  This was confirmed through a sensory evaluation by a set of panellists that commented on the soy frozen yoghurt flavour resembling that of soy ice cream with a beany flavour.   

 

The formulation also included alternative sweeteners such as sugar alcohols and stevia to achieve a ‘Low in Sugar’ claim.  It also achieved other claims such as being ‘Low in Fat’ and ‘High in Fiber’.   A first of such in our local market!

How Loss of Binding Protein Disrupts Brain Development of Mouse

A glimpse of my workplace. Left: Dry laboratory; Right: Wet laboratory

A sharing by Cheryl Phua, a 3rd year student from the Diploma in Veterinary Technology about her 26-week experience of Student Internship Programme (SIP) along with Major Project (MP).

 

The MP focused on the function of TDP-43, a deoxyribonucleic acid (DNA) / ribonucleic acid (RNA) binding protein that plays an important role in the development of the central nervous system (CNS), and this was further investigated in TDP-43 knock-out mice.  Both histological staining and immunofluorescence staining were performed on the brain tissues, and it was discovered that certain morphological deficiencies were present in the mutant mice embryos. The morphological defects discovered in the mutant mice include intracerebral haemorrhage, reduction of ganglionic eminence (GE), and thinning of the cortex.

 

For my SIP, I was given the roles and responsibilities like any other polytechnic intern at Prof. Ling’s Lab, and those were similar if not identical to that of a research assistant.  I was mainly assigned to investigate how the loss of TDP-43 in CNS precursors disrupts the development of the brain. For that, I needed to perform staining and quantification for an ongoing project in the laboratory. In addition, the day-to-day tasks included the upkeep of laboratory equipment and weaning the mice owned by the laboratory. 

 

During this attachment, I picked up some research techniques that I had not previously heard of.  These techniques were perfusion, immunofluorescence staining, and confocal microscopy imaging.  Although it was a steep learning curve for the first month of the attachment, I was able to adapt quickly and was soon assigned tasks that I was allowed to complete independently.  Apart from acquiring laboratory technical skills, I was also given many opportunities to improve my soft skills, such as my communication and presentation skills.  I greatly appreciated the chance to improve these skills as they are very much required for both my course of study, and when I enter the work force in the future.  The skills I had learnt during my two and a half years of studies (before the SIP) were also extremely helpful as we were taught many basic technical skills required for work in a laboratory, as well as how to handle different animals including mice. 

Turn Food Waste to Gold


Recycling food waste into useful products 

According to Singapore’s National Environment Agency (NEA), the amount of food waste generated in Singapore has increased by about 20 per cent over the past 10 years and is expected to increase with our growing population and economic activity. This is not only happening locally but regionally too. 

 

The current approach of disposing food waste is via incineration which is both wasteful and not sustainable. Various types of food waste have their unique properties and hence can be transformed to make a variety of useful products. 

Making compost from food waste
Sustainable building materials from food waste
Extraction of healthy compounds from fruit peels

Together with our research team from the Centre for Urban Sustainability (CUS), our students from the Diploma in Chemical Engineering did just that!  Through their involvement in various projects and adopting chemical and biological approaches, they learnt to turn post-consumption food waste from our canteens to compost.  They also used food by-products as part of making sustainable building materials, as well as used utilized fruit peels to develop some health products too!

Completed Major Project Titles

In Year 3, students undertake the module, Major Project (MP) to analyse current issues and provide innovative solutions to the industry.  Students are also given the opportunity to be cross-trained by taking on projects offered by other diplomas and their corresponding centres of excellence/ innovation. 

 

Have a glance at the hundreds of project titles that our students complete each academic year.  

No.

Major Project Titles

1

3D vascular spheroids as in-vitro tools to study the influence of indoxyl sulfate on vascular endothelium

2

3D vascular spheroids as in-vitro tools to study the influence of trimethylamine N-oxide on vascular endothelium

3

A comparison study on the evaluation of histopathology based on tissues associated to type 2 diabetic (T2D) rat model.

4

A convenient method for green water management

5

A handy guide to Alzheimer’s disease

6

A potential alternative to non-contact membrane striping system: contact membrane stripping system

7

A retrospective study of the prevalence and treatment of chronic kidney disease in canine and feline at the animal clinic

8

A retrospective study on the management of diabetic ketoacidosis in a 24-hour veterinary emergency hospital

9

A study on the effectiveness of skin and food sensitive diets on dogs with atopic dermatitis

10

A study on the prevalence and degree of compassion fatigue among veterinary technicians in Singapore

11

A study to determine the sampling efficiency for a new air sampler

12

A study to determine which part of the grooming session is the most stressful for dogs

13

All about DIY slimming

14

Alternate method to membrane striping for rapid test production

15

An investigation to compare protein lengths and amino acid composition between aerobes and anaerobes

16

Analysis and evaluation on the use of natural anti-inflammatory compounds in treatment of allergic contact dermatitis

17

Analysis of esterification process’ effluent COD

18

Analysis of span esters heating profile at esterification loop reactor

19

Analysis of the expression of alkane 1-monooxygenase 1, alkane 1-monooxygenase 2 and phenylacetaldehyde dehydrogenase from P. aeruginosa on the degradation of plastic

20

Analysis of the virulence characteristics of four soil bacterial isolates

21

Analysis of thermal stress on coral reefs: case study in Singapore and Southeast Asia region

22

Analytical accuracy of cellular identification in synovial fluid samples

23

Analytical method validation for carbimazole assay test using High-Performance Liquid Chromatography (HPLC)

24

Analytical method validation on carbimazole by UV-Vis

25

Anti-cancer activity of copper complexes

26

Application of fluidic and microfluidic in-vitro models to study bacterial migration in urinary catheters

27

Aquaponics - application assessment in water treatment

28

Assessment of anti-inflammatory and antioxidant properties of green mussels and coenzyme Q10 in laboratory rats

29

Assessment of the effects of stressful conditions on the carotenogenic activity of algae

30

Augmenting general public’s knowledge and compliance towards antibiotics in Singapore

31

Automation of Masson’s trichrome stain

32

Biodegradable polymers for medical applications

33

Buffer stock for aluminium cans and amber bottles and barcode scanning for stock withdrawal

34

Can the mouse grimace scale contribute to refinement of bleomycin-induced lung injury model?

35

Carbohydrate research and resistant starch analysis

36

Carbon absorption using microalgae

37

Characterisation and qualification of Lithospermum erythrohizon using LC-QTQF-MS

38

Characterisation of different water-based food gels using instrumental analysis and sensory evaluation

39

Characterisation of antibody-antigen interactions and interface profiling

40

Characterisation of protein-ligand interaction and interface profiling

41

Characterising the functional capacity of human Vδ2+ T cells in young and old

42

Characterising the functional capacity of Vδ1 & Vδ3 human T cells in young and old populations

43

Comparing the anti-bacterial properties of poly-imidazolium salts and iron core-shell materials

44

Comparison of different mating combinations and their effect on C57BL/6NTAC reproductive performance and pair mating as an alternative

45

Comparison of the concentration efficiency between PEG 8000 extraction and centrifugal filtration via qPCR analysis for virus in water

46

Comparison study of SBBR and MBBR – effects on nitrification and removal of micro-pollutants from water in a RAS

47

Correlating villus morphology to predict karyotype outcomes

48

Create a Patient Information Leaflet (PIL) to guide customers on the treatment options of constipation

49

Creating a GUT-SY online cooking series portfolio for the healthy gut and overall wellness

50

Design and construction of flavivirus infectious clones

51

Detection of living micro-invertebrates in water samples

52

Develop reference materials for PAs on nutritional feeds for specific types of patients

53

Developing a Patient Information Leaflet (PIL) on osteoarthritis treatment

54

Developing an education leaflet for public regarding supplements for osteoporosis and osteoarthritis

55

Developing educating materials regarding benefits of common TCM products for public

56

Developing Quality Manual following ISO13485:2016 for medical device distribution organisation

57

Developing training materials on osteoporosis treatment for patients

58

Development and optimisation of topical semi-solid preparation containing natural extract

59

Development and shelf-life study of jams

60

Development of a leaflet to educate public about glucosamine use in osteoarthritis

61

Development of a leaflet: choosing joint pain supplements

62

Development of a patient information leaflet to educate the public about osteoarthritis and rheumatoid arthritis

63

Development of a video to educate the public on SARS

64

Development of an efficient online file and folder management system with QR code capabilities to enable seamless document access for a pharmaceutical manufacturer.

65

Development of ant kit and sea monkey kit

66

Development of Asian recipes using local underutilised plant species

67

Development of chromatographic purification process of protein from harvested cells

68

Development of educational and recipes videos on texture-modified meals

69

Development of fluorescent paper-based assay

70

Development of freeze-thaw stable savoury baked products for tea refreshment catering

71

Development of healthier noodles/pasta recipes for Bistro Lab

72

Development of healthier one-pot meals for Bistro Lab

73

Development of healthier recipes for primary school children

74

Development of healthier rice/grains recipes for Bistro Lab

75

Development of high resolution melting assay for the detection of Vibrio parahaemolyticus strains

76

Development of Infoweb for the management of hypertension

77

Development of interactive nutrition/ health promoting games for a learning app

78

Development of low Glycaemic Index (GI) pao

79

Development of materials to educate the public on COVID-19

80

Development of materials to educate the public on dengue

81

Development of materials to educate the public on haze

82

Development of materials to educate the public on malaria

83

Development of patient education videos for major depressive disorder

84

Development of Patient Information Leaflet (PIL) to raise awareness on irritable bowel syndrome

85

Development of plant-based products

86

Development of post-op recipes (different stages) for bariatric surgery patients in a local hospital

87

Development of PPE communication tool

88

Development of recipes using sea grapes (Caulerpa lentillifera) as an ingredient

89

Development of South Asian street food recipes for the street food vendors

90

Development of TP low Glycaemic Index (GI) recipe book

91

Development of training materials for pharmacy assistants (PAs) on travel related medicines

92

Development of vegan cheese

93

Development of vegan recipes for Bistro Lab

94

Development of videos and e-booklet on food safety practices for food vendors

95

Differences in the rate of learning between different canine training techniques

96

Earthworms as alternative source of protein for fish feed

97

Educating newly diagnosed breast, prostate, colorectal and lung cancer patients on the management of side effects associated with chemotherapy

98

Educating pharmacist assistants (PAs) on OTC medication

99

Educating public on preparation of MERS outbreak in Singapore

100

Educating the public on management of eczema

101

Educating the public on the treatment of common skin conditions: acne

102

Educating women on oral contraceptives

103

Effect of carotenoid diet in the sexual selection of cherry shrimp

104

Effect of husbandry and experimental procedures on incidences of male mouse aggression in the bleomycin-induced lung injury model

105

Effect of novel ingredients at different concentrations on quality and shelf-life of cupcakes

106

Effect of PGR application on physiological characteristics of a plant

107

Effect of probiotic enrichments on the density and growth rate of live feed

108

Effectiveness of nano-bubbles in the removal of aquaculture sludge

109

Effects of Chenopodium quinoa extracts on human skin homeostasis and aging

110

Effects of different media and temperature on microgreen growth and nutritional value

111

Effects of different types of medium on in-vitro asymbiotic seed germination of orchid spp.

112

Effects of light and CO2 concentration on growth of Spirulina

113

Effects of nano-bubble technology on water in aquaculture and potential for sludge treatment

114

Effects of storage time and temperature on urinalysis values from zoo animals

115

Effects of tank lighting on the occurrence of shock syndrome in orange-spotted grouper, Epinephelus coioides larviculture

116

Effects of the addition of bio-enrichment in the diet on growth rate of shrimps

117

Effects of water quality on Vannamei shrimp growth

118

Effects on application of quantum grow bacterial consortium on vegetables grown in aquaponics system

119

Efficacy of fresh diets in managing gastrointestinal sensitivities in dogs

120

Efficiency of microplastic removal by mussels in climate change events

121

Establishment of cycle time reduction for the assembly line of Fortitude 2.1 test kits

122

Evaluating antimicrobial properties of polystyrene copolymers

123

Evaluation of key volatiles of matcha and synthesis of matcha flavour

124

Evaluation of procedures of Single-Use Technologies (SUTs) of past and existing processes in mammalian cell therapy and, cell and gene therapy manufacturing sites of Singapore

125

Evaluation of selected silicones and additives improving compression set

126

Evaluation of stress conditions for optimal carotenoid production in D. salina

127

Evaluation of the correlation between ATP monitoring, coliform count and aerobic count

128

Evaluation of the effects of ketamine-medetomidine-butorphanol drug combination as an anesthetic protocol for feline ovariohysterectomy

129

Evaluation of the protective roles of short chain fatty acids on dysfunctional vascular cells.

130

Evaluation of the uses of canine hydrotherapy in Singapore

131

Evolutionary conservation of stop codon

132

Exercise and nutrition for people with diabetes

133

Exploring the effects of Fecal Matter Transplant (FMT) in global ischemic mice model

134

Exploring the histopathological changes in selected mouse models

135

Factors affecting prevalence of recurring canine otitis externa in Singapore

136

Factors influencing the choice of oral health products used among the population in Singapore

137

Fecal microbiota transplantation (FMT): improving the methods of FMT recruitment and success, and discussing the super-donor phenomenon

138

Feline lower urinary tract disease (FLUTD): a retrospective study of the prospective risk factors for recurrences.

139

Formulation and sensory evaluation of low Glycaemic Index (GI) bun with functional ingredient

140

Formulation of feed for marble goby larvae

141

Freeze-dryer qualification and preparation of E. coli biomass evaluation for lyophilized stock buffer

142

Functional validation of nano-bubble generators

143

Getting in the know about depression

144

Growth efficiency of orchid seeds in different media

145

Growth in sales in the medical industry through social media marketing

146

Harnessing the heterogeneity of macrophages to fight cancer

147

Hazard Analysis and Critical Control Points (HACCP) in food safety management of Bistro Lab

148

Heterotrophic cultivation of Chlorella

149

How does dog daycare contribute to pets' physical and mental well-being

150

How K5 + safety and ISO 45001:2018 has contributed in upholding quality assurance

151

How well treated can fish water be?

152

Identification of probiotics and effects of prebiotics on the gut microbiome of shrimps

153

Identifying the role of protein kinase in glucose deprivation-induced cancer cell death

154

Immuno-monitoring immune genes in fish fed with worms on plastic diet

155

Improve efficiency in releasing of products

156

Improvement of the quality and shelf-life of bread using fermented flour

157

Improving the ability of a zooplankton to promote growth and survival rate in mud crab zoea

158

Improving the diets of type 2 diabetic patients through digital health

159

Improving the inspection of incoming material to minimize pest infiltration

160

Increasing efficiency to evolve into a high-performance laboratory by reducing time consumption

161

Insights into the evolution of bacteria response to phages using CRISPR systems from longitudinal microbiomes

162

Interference of heparin and propofol on APTT-based clot waveform analysis

163

Inventory management in COVID-19 clinical laboratory

164

Investigation into the effect of coral fragment size and feeding on growth

165

Investigation of insulin resistance associated with pancreatic biomarker gene expression and the longitudinal relationship of gut microbiota in diabetic rat model

166

Investigation on efficiency of Chlorella beads in green water

167

In-vitro evaluation across brands of Paracetamol tablets available in retail pharmacies

168

Isolation and characterisation of novel pigmented bacteria

169

Isolation and characterisation of novel pigmented bacterium

170

Isolation and identification of gram-positive and gram-negative bacteria in food, cosmetics and water samples

171

Isolation of probiotics and the effects of diet on the canine gut microbiome

172

Kaizen: checklist review comments status tracker via digital platform

173

Large scale protein production for drug target

174

Locally-adapted and indigenous plant species

175

Managing canine renal insufficiencies with fresh foods

176

Market analysis on competitive skincare products

177

Method of ammonification treatment to remove nitrogen from recirculating water used in aquaculture system

178

Normal radiographic reference values of cardiac silhoutte in parrots specifically amazons, macaws and cockatoos

179

Ocean acidification matters: the effect of low pH on the reproductive success and larval development of giant clam, Tridacna crocea

180

Optimal time of surgery for neon-natal hernia

181

Optimisation of DNA synthesis and assembly technologies for designer microbes

182

Optimisation of indoor culture techniques on the survivability of blood clams

183

Optimise parameters for growth of probiotics

184

Optimising the germination and growth of the Mertensia maritima plant

185

Optimising the space in the SOM lab compactors

186

Optimisation of COVID-19 test kit production

187

Optimisation of COVID-19 test kit quality control

188

Optimisation of protocol for vaccination and heartworm preventative reminders in veterinary practices

189

Optimisation of transformation techniques for developing designer microbes for the production of commercially important products

190

Optimising the use of dosing machine

191

Parent’s knowledge of self-medication for flu and cold for their children

192

Patient Information Leaflet (PIL) on migraine pain management

193

Pediatric oncology nutrition training materials

194

Persea americana seeds as high value food

195

Post-treatment management of male cats with feline urologic syndrome

196

Preparation of suitable media for producing cordyceps to generate food ingredients from fruit waste

197

Prevalence and severity of periodontitis in diabetic patients in Singapore

198

Probiotics for fish’s feed

199

Process monitoring control for dry blending – blender 1, 2, 3 and 4

200

Producing GFP-expressing Enterovirus D68 (EV-D68)

201

Production of probiotics from agricultural waste

202

Production of rapid test reagents

203

Production optimisation of cordyceps protein as potential anti-microbial compound

204

Profiling LAG3 immune cells as a predictor of immunotherapy responsiveness in hepatocellular carcinoma

205

Profiling of microbiome in diabetes mice models

206

Profiling of microbiome in post-depression mice model

207

Public education on cold, flu and allergic rhinitis

208

Public perception of health supplements

209

Public's awareness and knowledge about dry eyes and its management in Singapore

210

Public's awareness and knowledge about hair loss and its management in Singapore

211

Public's perception on self-management of simple acute wounds at home

212

Qualification of Ksuk liquid filling and capping machine for the production of western blot and ELISA controls

213

Qualification of manufacturing clean room and equipment

214

Quality improvement project for a local hospital dietetics department

215

Raising awareness of generics in retail pharmacies

216

Raising awareness of Nicotine Replacement Therapy (NRT)

217

Raising awareness of stroke

218

Raising public awareness of proper wound management

219

Raising public awareness on the importance of travel medicines

220

Recombinant collagen methacrylate hydrogels for tissue engineering applications

221

Reducing human errors to achieve higher efficiency and high-performance laboratory

222

Reduction of size change timing in packaging lines

223

Reduction of time taken for full course cleaning in stickpack and pouch line

224

Reference products developed for authentication of TCM granules

225

Repurposing of an thalidomide

226

Repurposing of aspirin

227

Repurposing of sildenafil

228

Research and development of algae-based biofilm for aquaculture water treatment

229

Research and development of anammox used in Recirculating Aquaculture Systems (RAS)

230

Research on how different stock density affects water treatment efficiency of a spinning bed bioreactor in a RAS

231

Research on microorganism levels in different areas of RAS system

232

Retrospective study  on a dog's diet and dental care and its effects on the dog's overall health

233

Retrospective study of diagnosis and management of chronic kidney disease

234

Role of BUB1B protein in skin homeostasis and aging

235

Rosemary extract as an antioxidant in fish oil

236

School canteen improvement project

237

Screening and identification of novel pigment-producing bacteria from the environment

238

Screening of anti-cancer activity from mushroom secondary metabolites

239

Screening of anti-cancer activity from plant and fungal secondary metabolites

240

Screening of anti-cancer activity in lemongrass and longevity spinach extract with MCF-7 cells using MTT assay

241

Screening of anti-cancer activity of plant and microbial secondary metabolites

242

Seed germination of orchid species using different media types

243

Sequence similarity networks and their application in microbiome analysis

244

Setting up a pineapple processing plant

245

Shelf-life extension of emulsified butter

246

Shelf-life extension of fish and chips batter

247

Smoking and gut microbiome

248

Soil microbiome profiling and its role in nutrition and extension of shelf-life of vegetables

249

Standing-bending films in EOS for the evaluation of spinal flexibility in scoliosis

250

Study of encysted Metacercariae and its medicated treatment efficacy in ornamental freshwater fish

251

Study of the factors that affect the effectiveness of Cushing’s disease treatment in canines

252

Study of the prevalence and treatment of obesity-induced osteoarthritis of dogs in Singapore

253

Study on consumer perception and behaviour concerning health supplements for management of chronic illness

254

Study on effects of pasteurisation on algae removal

255

Study on in-vivo skin sensitization using reconstructed human epidermis and analysis by RT-PCR

256

Study on plant growth performance of Pak Choy incorporation with microbial concoction in soilless culture

257

Study the plant growth performance of Chye Sim incorporation with microbial concoction in soilless culture

258

Studying of trends in fish growth and mortality

259

Studying the health literacy in Singapore and customer’s understanding of over-the-counter (OTC) medication for the treatment of gastric pain

260

Studying the level of understanding towards cough and cold over-the-counter (OTC) medication

261

Studying the role of TP53 on hepcidin-mediated macrophage polarization

262

Suitability of fragrances for all skin types

263

Techniques employed to provide customer satisfaction at retail pharmacies

264

Telemedicine: an innovative addition to the veterinary industry in Singapore

265

The effect of diet on dental and gastrointestinal diseases in Oryctolagus cuniciulus domesticus

266

The effects and treatment of lens luxations on Canis familiaris

267

The effects of anammox on the nitrification and denitrification process in RAS

268

The effects of calcium concentration on shrimp's growth rate.

269

The effects of exogenous application of PGR on the growth and development of a plant

270

The effects of growth and storage conditions on the storage viability of fungal spores

271

The effects of probiotics on the growth rate and survivability of shrimps

272

The effects on application of quantum grow bacteria consortium on vegetables in aquaponics system

273

The immunological effects of pharmaceutical drugs, social isolation and musical influence on beneficial worms

274

The impacts of online patient education videos on the layperson’s ability to correctly administer epinephrine injections, ear preparations, nasal sprays and washes.

275

The implication of transforming growth factor beta (TGFB) signaling pathway in the malignancy of colorectal cancer

276

The level of expression of MBNL1 in normal and type 2 diabetic (T2D) aortic smooth muscle cells.

277

The neurological effects of Fecal Matter Transplant (FMT) from normal mice onto recipient post-stroke depressed mice

278

The role played by chromatin remodeler, BAZ2B, in epidermal self-renewal

279

The study of dwarf gourami (Colisa lalia) diseases and treatments from ornamental fish farms

280

The study of embryonic development and the effects of probiotics on freshwater prawns

281

The study of the effects prebiotics in food wastes have on the growth of probiotics and potential pathogens

282

The study on the effects of systemic inflammation in global ischemia mouse model

283

The uses of probiotics

284

Therapeutic effect of phytopharmaceuticals with essential oil on antibiotics resistance

285

Therapeutic guidelines on smoking cessation

286

Therapeutic potential of compound 17b in the treatment of hypertension and its associated complications in the liver

287

To assess the effectiveness of the Patient Information Leaflet (PIL) in educating patients on the treatment of lower back pain

288

To create awareness to general public on menopause information

289

To optimise the production and extraction of nutrients from a microalgae

290

To prepare a question and answer guide for pharmacy assistants on the management of dyspepsia

291

Traditional recipes of local Eurasian and Indian snacks

292

Tropical fruit by-products to functional food ingredients (microbial protein)

293

Troubleshooting of calibration standard stocks using ICP-OES for the determination of trace calcium content in urea

294

Understanding the mechanisms through which NRF2 is regulated

295

Understanding the regulatory mechanism and activation of NRF2 for the development of more effective NRF2-targeted therapeutics

296

Use of alternative tests to substitute titration for the determination of peroxide values of selected vegetable oils.

297

Use of commercial peroxide test to determine peroxide values of fish oil

298

Use of Rosemary extract to delay oxidation of fish oil

299

Use of sodium percarbonate and peracetic acid for disease management in aquaculture

300

Use of TCM in children

301

Utilizing wastes-fed superworms in achieving a sustainable circular economy in urban farming

302

Vaccinations recommended for Singaporeans when travelling

303

Validation of a fully-automated clinical nucleic acid extraction system

304

Validation of BD (Becton Dickinson) MAXTM multi-drug resistant tuberculosis assay for non-sputum samples

305

Validation of control measures in Food Safety Management System (FSMS)

306

Validation of in-house produced E. coli biomass – real time study

307

Vermicomposting of different food waste with Malaysian blue earthworm and its effect

308

Working towards a circular economy: from plastic wastes to plant fertilisers and fish feeds

309

Young adults’ perceptions of the prevalence of high cholesterol

No.

Major Project Titles

1

An experimental study on thermal conductivity and fire-resistance of concrete incorporated with recycled plastics

2

Automated robotic liquid handling system for downstream processing

3

Characterisation and sensitivity analysis of High-Density Polyethylene (HDPE) from waste streams incorporated in concrete for a sustainable built environment

4

Characterisation and sensitivity analysis of Low-Density Polyethylene (LDPE) from waste streams incorporated in Concrete for a sustainable built environment

5

Characterisation and sensitivity analysis of Polyethylene Terephthalate (PET) from waste streams incorporated in concrete for a sustainable built environment

6

Characterisation and sensitivity analysis of Polypropylene from waste streams incorporated in concrete for a sustainable built environment

7

Characterisation of Concentrated Recyclable Ash (CRA) as raw materials for sustainable building products

8

Chemical separation of hazardous chemicals in oil industries

9

Chrome, cadmium and nickel plating

10

Comparative study of material selection and generic corrosion control in a petrochemical plant

11

Comparing the two procedures, UOP 46-64 and UOP 46-85 of UOP method 46: paraffin wax content of petroleum oils and asphalts

12

Comparison of manual and automatic Pensky-Martens closed cup tester

13

Contamination detection and analysis of lubricants

14

Conversion of food waste into fish feed and growth media for probiotic bacteria

15

Correlation study on total organic carbon (TOC) to chemical oxygen demand (COD) of effluent

16

Cost-effective extraction of dietary fibre from fruit peels

17

Design and operation of statistical quality control (SQC) in micro carbon residue (MCR)

18

Determination of heavy metals in plastics digested by microwave and examined by inductively coupled plasma optical emission spectroscopy (ICP-OES)

19

Determination of wear caused by water contamination

20

Develop database of individual bacteria colonies for artificial intelligence colony counter

21

Developing new biocatalysts for facilitated composting from food waste

22

Distillation of petroleum products and liquid fuels at atmospheric pressure

23

Effects of intermittent flow on quality of drinking water

24

Efficiency and accuracy of viscosity instruments

25

Elimination of tag masks on reptile skins

26

Enhancing of colony database for a SMART colony counting device

27

Environmental monitoring documentation process optimization

28

EUV mask blank production integration: full integration flow

29

EUV mask blank production integration: individual process defect control

30

Evaluating engine performance with soot analysis

31

Evaluating lithium ferrocyanide as an electrolyte

32

Evaluation of effect pigment performance on injection moulding process

33

Evaluation of test oils

34

Fermentation of fruit wastes into sustainable cleaning agents

35

Formulation, production and assessment of the effectiveness of the alcohol-based hand sanitizer with presence of other additives

36

Functional coatings

37

Helping in the development of Insta-ColR

38

Identification and measurement of microplastics

39

Identification of nutrients and metals in drinking water

40

Implementation of mass balance templates for process optimisation

41

Implementation of Quality Alert System within the supply chain

42

Improvement in plant and equipment processes

43

Improving documentation abilities in the Petrochemical Industry

44

Incorporation of Concentrated Recyclable Ash (CRA) in concrete for sustainable building products

45

Influence of ashing content and element concentration of residual fuel oil from external factors

46

Ion chromatography process, automation and optimization

47

Life cycle assessment of recycling mixed-plastic wastes into raw building ingredients: a case study in Singapore

48

Life cycle assessment of utilization of mixed-plastic wastes in sustainable concrete materials: a Singapore case study

49

Manufacturing defect of alligator skins – folded line

50

Mechanism between pigment and polymers

51

Mesophilic anaerobic digestion of sludge at low SRT

52

Method validation of dissolved organic carbon in all types of water using TOC Analyzer

53

Method validation of total organic carbon in all types of water using TOC analyzer

54

Method validation update on the determination of PBB/PBDE in polymers by GC-MS

55

Natural and eco-friendly cleaning agent

56

Natural larvicidal formulation incorporation in water absorbent hydrogel

57

Optimisation of surface chemistry on ship hulls

58

Optimization of ASTM D6304

59

Optimization of ASTM D664

60

Optimization of biological filtration system using different substrates as carbon source

61

Optimization of checklist for classified areas in production buildings

62

Optimization of food waste in-vessel composting of Asian food waste

63

Optimized detection of indicator bacteria in water sources.

64

Parameter testing of swimming pool water

65

PET UV blocker Masterbatch for window film

66

Plant condition monitoring locations review

67

Production of animal feed and synbiotics from recycled food waste

68

Production of fertiliser from food waste

69

Quality assurance: calibration and maintenance of glassware and Statistical Quality Control of potassium hydroxide

70

Quality control of Lonicerae japonicae flos (金銀花) using HPLC, HPLC Q-TOF-MS and HPLC QQQ-MS

71

Raw materials characteristic data analysis

72

Redox-targeting process approach on recycling spent LiFePO4 batteries 

73

Re-qualification and validation of pH/conductivity meter in quality control laboratory for biopharmaceutical industry

74

Research on how lab testing of water samples from cooling tower depicts the condition of the cooling tower

75

Revision and monitoring of master data

76

Sample preparation methods for ICP-OES 

77

Simplification of operational checklist

78

Small scale column packing for chromatography process

79

Study between the different types of Interferences affecting the sulfur content in petroleum products

80

Study of challenge face from manual work to process automation in shop floor

81

Study of fame acid and compost using earthworms

82

Study on efforts to mitigate single-use technology in biopharma industries

83

Sustainable upcycling of fruit by-product into functional food ingredients

84

Testing of marine fuels by standard and non-standard methods

85

The development of effective and cost-efficient cleaning agent through fruit waste fermentation

86

The effect of different types of food waste on earthworm growth

87

The effect of pigments in blocking UV radiation on PET film

88

The importance of piping inspection in the petrochemical industry

89

Thermal degradation of fuel oil and its effects on different test methods

90

Validity of test method for determination of sulfate content in potassium sulfate and ammonium sulfate

No.

Major Project Titles

1

A quick beginner's guide in Power BI

2

A study on the use of AI for development of CHE training/ educational materials

3

Alternative method for acid washing

4

Bringing education online due to a pandemic

5

Checklist for health supplement registration

6

Development of a process control and instrumentation database before integration into a chatbot system

7

Development of PPE communication tool

8

Enhance the stability and shelf-life of the laboratory reagents

9

Equipment commissioning in cell processing room

10

Establishing contact tracing framework for Applied Science School (ASC)

11

Establishing standard operating procedures in the cleanroom

12

Evaluating the possibility of cutting laminated cards in non-humidity controlled environment

13

Improvement of GMP training process

14

Improving on technical report template

15

Improving the workflow of In-Process Testing (IPT)

16

Improving training procedures and materials to enhance human performance

17

Increasing awareness and profit through marketing kits

18

Increasing organic food product profits on e-commerce platforms and growing the business brand

19

Long-term asset replacement

20

Operations management for an applied material laboratory - system for optimal productivity

21

Optimisation of column packing

22

Optimisation of database marketing to improve competitiveness on E-commerce platforms

23

Promoting TraceTogether in Temasek Polytechnic

24

Quality management and risk analysis of an integrated laboratory information management system

25

Review on CBRN awareness lectures conducted at a local training school

26

Revision and implementation of tools for accurate master data

27

Setting up e-commerce, streamlining operations and improving marketing for a food business

28

Simple starter guide for Power BI

29

Study on data analysis of steam tracing

30

Use Of ATP monitoring device in checking hygiene status of high touch areas

31

Use of Excel macros to enhance productivity on current subject assignment programme

32

Use of VBA for productivity enhancement

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