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Overview 

Mission

 

This Centre brings together scientists and engineers to pursue translational research and develop practical applications to improve human health and well-being.  It also supports staff capability development as well as teaching and learning activities by providing the necessary platforms and expertise

About the Centre

 

This is a multi-disciplinary centre focusing on the development of BioMEMS (Biomedical micro-electro-mechanical systems) based healthcare devices and systems.  The centre continuously grows its research & development (R&D) capabilities in biosensors, microfluidics, and wearable healthcare sensors.

The Centre has secured various competitive R&D grants and established strategic partnerships with industry companies and research institutes, and has strong capabilities in developing innovative devices and systems from concept to field-deployable prototypes.

Core Technology

The Centre focuses on developing BioMEMS (Biomedical micro-electro-mechanical systems) based innovative devices for healthcare applications:

Biosensor for point-of-care diagnostics

 

  • Localised Surface Plasmon Resonance (LSPR) biosensors
  • Microelectrode biosensors
  • Surface Acoustic Wave (SAW) biosensors

 

 

Microfluidic devices for miniaturised chemical and biological testing 

 

  • Development of microfluidic devices with integrated functional components
  • Development of new chemical/biological testing protocols on a microfluidic platform
  • Fabrication of microfluidic products using industrial-standard materials and methods 

Wearable sensors for healthcare applications

 

  • Development of a wide range of microfluidic pressure sensors for healthcare applications from TCM Pulse Analyzer to ‘Tui Na’ Robot
  • Development of flexible pressure sensors based on different conductive materials
  • Development of intelligent wearable healthcare products

Anti-viral and anti-bacterial respirator (AVR)

 

  • Functions as a personal wearable respirator
  • Employs a novel combination of air filtration, antiviral coating, and germicidal irradiation technology.
  • Eliminates the limitations of using high power in a heavy device normally required for inactivation of  viruses and achieves superior air-cleansing performance.
  • Able to block or inactivate about 99% of viruses belonging to the family MERS-CoV and Influenza A, and up to 95% of particulates in the range of 0.3 to 10.0 microns

Projects

Industry Partners

The Centre works with various industry and academia partners on knowledge sharing, technology exchange, or collaboration projects.  Some of our partners include: 

Publications

Publications in the Media

 

An article featuring a revolutionary blood testing system prototype jointly developed by Temasek Polytechnic, A*STAR’s Institute of Materials Research and Engineering (IMRE), and Tan Tock Seng Hospital (TTSH), which can accelerate medical diagnosis, was featured in Lianhe Zaobao on 12 Aug 2016.

 

 

Papers Presented/Published

 

  • L. L. Sun, Y. S. Leo, X. D. Zhou, W. Ng, T. I. Wong, J. Deng, Localized surface plasmon resonance based point-of-care system for sepsis diagnosis, Materials Science for Energy Technologies 3 (2020) 274–281.
  • L. L. Sun, Biosensor and microfluidic chip based Point-of-care systems for disease diagnosis, 12th International Conference on Ceramic Materials and Components for Energy and Environmental Applications (CMCEE 2018) Singapore, 22-27 Jul 2018 (invited).
  • L. L. Sun, “Biosensor and microfluidic chip based Point-of-care systems for disease diagnosis”, The 7th International Multidisciplinary Conference on Optofluidics 2017, 25 Jul 2017, Singapore, (Invited).
  • Y. Fu, “Centrifugation-enhanced enzyme immunoassay for rapid bacteria detection in common laboratory tube”, The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017, 22-26 Oct 2017, USA.
  • J. Deng, T.I. Wong, L. L. Sun, C.G. Quan, X. D. Zhou, “Acceleration of e-beam lithography by minimized resist exposure for large scale nanofabrication, Microelectronic Engineering”, Microelectronic Engineering 166 (2016) 31–38.
  • T. I. Wong, J. Limantoro, K. P. Fong, C. Y. L. Tan, C. G. Quan, L. L. Sun and X. D. Zhou, “Easy fabrication of high quality nickel mold for deep polymer microfluidic channels”, J. Micromech. Microeng.26 (2016) 065016.
  • R. Riazul, Y. Fu, L. L. Sun, “Silver Enhanced Immunoassay for Escherichia coli Rapid Detection”, International Research Symposium on Engineering and Technology (IRSET) 2016, 13-15 September, 2016.
  • Y. Fu, R. Raziq, H. Miao, Y. Yang, M. H. Kuok, N. C. Tan & L. L. Sun, “Rapid urinary bacteria detection using DEP-enhanced microfluidic immunocapture assay”, The 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Korea, 25-29 October, 2015.

 

Patents

  • “Detection of Salmonella Using Immunomagnetic Separation and Qdot Fluorescent Assay”, Singapore provisional patent Application No.: SG10201910341T, Filing Date: 06 Nov 2019.
  • “Biomarker Detection System”, PCT/SG2017/050372, Filing Date: 21 July 2017.
  • “Microfluidic system with dielectrophoresis on-chip concentration module”, SG provisional patent No.: 10201706170X, Filling Date: 28 Jul 2017.
  • “A novel laser assisted chemical etching method for GaN”, SG provisional patent No.: 10201706171X, Filling Date: 28 Jul 2017.
  • “Plasmonic biosensing based microfluidics point-of-care system for procalcitonin detection”, Singapore provisional patent application No: 10201606001Q, Filing Date: 21 Jul 2016.

 

Our Team

Contact Details

  • Dr Sun Ling Ling
  • 67806624
  • 8.30 am to 6.00 pm (Mon to Fri). Closed on Sat, Sun & Public Holidays
  • Centre under School of Engineering

    Temasek Polytechnic
    West Wing Block 34, Level 1, Room 28
    21 Tampines Ave 1
    Singapore 529757

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